miRBooking-scan explore miRBooking 2.0 predictions

The miRBooking-scan Web service provides an exploratory view of reference microtargetomes computed by miRBooking 2.0.

Not interested in MCF-7? Choose a different cell line.

MCF-7 ENCSR247DVY from ENCODE

Breast cancer cell line isolated in 1970 from a 69-year-old Caucasian woman.

Here's how you can reproduce this:

mirbooking --relative-cutoff=0 --mirnas=data/mature.fa --5prime-footprint=9 --3prime-footprint=7 --targets=data/gencode.v24.transcripts.fa --tolerance=1e-8 --supplementary-model=yan-et-al-2018 --supplementary-scores=data/scores-3mer --seed-scores=data/scores-7mer-3mismatch-centered --cutoff=100 --input=ENCSR247DVY.tsv

Note that only interactions expected to reach at least 100 pM under ideal conditions were considered in this model.
Occupant target_name miRNA Name Bound Fraction Efficiency
MIMAT0000076::ENST00000373316.4 PGK1 hsa-miR-21-5p 48.15% 48.67%
MIMAT0000076::ENST00000368830.7 MRPL9 hsa-miR-21-5p 37.73% 48.25%
MIMAT0000076::ENST00000336133.7 SARNP hsa-miR-21-5p 37.72% 48.24%
MIMAT0000076::ENST00000414487.6 SNRPE hsa-miR-21-5p 35.08% 35.73%
MIMAT0000076::ENST00000249289.4 ATP6V1F hsa-miR-21-5p 35.07% 35.72%
MIMAT0000076::ENST00000223641.4 SEC61B hsa-miR-21-5p 35.06% 35.72%
MIMAT0000076::ENST00000262942.9 ARPC1A hsa-miR-21-5p 34.97% 35.62%
MIMAT0000076::ENST00000328848.5 NOP10 hsa-miR-21-5p 33.64% 34.3%
MIMAT0000076::ENST00000455959.7 SEC11A hsa-miR-21-5p 33.47% 34.1%
MIMAT0000076::ENST00000394609.6 RTN4 hsa-miR-21-5p 32.45% 47.9%
MIMAT0000076::ENST00000591645.1 TPM4 hsa-miR-21-5p 31.03% 37.65%
MIMAT0000076::ENST00000262213.6 TRAM1 hsa-miR-21-5p 30.39% 31.08%
MIMAT0000076::ENST00000357214.5 SFPQ hsa-miR-21-5p 29.98% 45.07%
MIMAT0000076::ENST00000302763.11 CTNNA1 hsa-miR-21-5p 28.99% 44.7%
MIMAT0000076::ENST00000256689.9 SLC38A2 hsa-miR-21-5p 27.98% 35.5%
MIMAT0000076::ENST00000313115.10 ATOX1 hsa-miR-21-5p 27.95% 28.68%
MIMAT0000076::ENST00000250448.2 FOXA1 hsa-miR-21-5p 27.78% 28.52%
MIMAT0000076::ENST00000367274.8 UBE2T hsa-miR-21-5p 25.9% 31.38%
MIMAT0000076::ENST00000393436.9 RAP1B hsa-miR-21-5p 24.03% 48.24%
MIMAT0000617::ENST00000394815.2 KRT80 hsa-miR-200c-3p 24.03% 27.6%
MIMAT0000076::ENST00000548752.6 CHURC1 hsa-miR-21-5p 22.29% 23.07%
MIMAT0000076::ENST00000610907.1 PABPC1 hsa-miR-21-5p 21.89% 35.64%
MIMAT0000076::ENST00000315091.7 TARDBP hsa-miR-21-5p 21.76% 22.55%
MIMAT0000076::ENST00000306368.8 RNF181 hsa-miR-21-5p 21.75% 22.54%
MIMAT0000076::ENST00000083182.7 APPBP2 hsa-miR-21-5p 21.51% 36.92%
MIMAT0000076::ENST00000329421.7 MARCKSL1 hsa-miR-21-5p 21.35% 44.83%
MIMAT0000076::ENST00000225603.8 CBX1 hsa-miR-21-5p 21.14% 21.93%
MIMAT0000076::ENST00000216832.8 PNN hsa-miR-21-5p 20.97% 44.93%
MIMAT0000076::ENST00000474024.5 DSTN hsa-miR-21-5p 20.14% 35.49%
MIMAT0000076::ENST00000556866.5 AHSA1 hsa-miR-21-5p 20.13% 35.65%
MIMAT0000076::ENST00000396821.7 DDX17 hsa-miR-21-5p 19.86% 28.52%
MIMAT0000076::ENST00000358888.7 RPL41 hsa-miR-21-5p 19.77% 35.68%
MIMAT0000076::ENST00000292644.4 PSMC2 hsa-miR-21-5p 19.67% 20.48%
MIMAT0000076::ENST00000370089.6 COX7A2 hsa-miR-21-5p 19.67% 20.47%
MIMAT0000076::ENST00000372134.5 GHITM hsa-miR-21-5p 19.64% 20.45%
MIMAT0000076::ENST00000481898.5 LRRC75A-AS1 hsa-miR-21-5p 18.59% 22.49%
MIMAT0000076::ENST00000014914.5 GPRC5A hsa-miR-21-5p 18.18% 47.23%
MIMAT0000076::ENST00000359543.7 EMP2 hsa-miR-21-5p 18.18% 28.43%
MIMAT0000076::ENST00000264108.4 HAT1 hsa-miR-21-5p 17.99% 37.55%
MIMAT0000076::ENST00000393263.7 NAP1L1 hsa-miR-21-5p 17.88% 37.22%
MIMAT0000076::ENST00000361789.2 MT-CYB hsa-miR-21-5p 17.29% 56.06%
MIMAT0000076::ENST00000303436.10 ARF4 hsa-miR-21-5p 17.26% 18.09%
MIMAT0000076::ENST00000436459.2 EEF1A1P5 hsa-miR-21-5p 17.25% 18.08%
MIMAT0000076::ENST00000265087.8 STC2 hsa-miR-21-5p 17.14% 44.82%
MIMAT0000076::ENST00000517603.5 UQCRB hsa-miR-21-5p 16.59% 25.9%
MIMAT0000076::ENST00000398637.9 SLC38A1 hsa-miR-21-5p 16.22% 28.36%
MIMAT0000076::ENST00000373212.5 SH3BGRL hsa-miR-21-5p 15.88% 35.45%
MIMAT0000076::ENST00000620941.1 SRSF3 hsa-miR-21-5p 15.73% 28.66%
MIMAT0000076::ENST00000396222.6 LDHA hsa-miR-21-5p 15.51% 16.36%
MIMAT0000076::ENST00000262067.4 TSPAN13 hsa-miR-21-5p 15.51% 16.36%

Download this view in TSV:

curl -H Accept:text/tab-separated-values 'https://major.iric.ca/~poirigui/cgi-bin/mirbooking-scan/app.cgi/cell-lines/ENCSR247DVY'

Cite us

miRBooking 1.0: Weill N, Lisi V, Scott N, Dallaire P, Pelloux J, Major F. MirBooking simulates the stoichiometric mode of action of microRNAs, Nucleic Acids Res. 2015 43(14):6730-8.

miRBooking 2.0: Publication upcoming!