miRBooking-scan explore miRBooking 2.0 predictions

The miRBooking-scan Web service provides an exploratory view of reference microtargetomes computed by miRBooking 2.0.

Not interested in HeLa-S3? Choose a different cell line.

HeLa-S3 ENCSR068MRQ from ENCODE

Immortalized human cell line derived from cervical cancer cells.

Here's how you can reproduce this:

mirbooking --3prime-footprint=7 --5prime-footprint=9 --seed-scores=data/scores-7mer-3mismatch-centered --supplementary-scores=data/scores-3mer --tolerance=1e-8 --targets=data/gencode.v24.transcripts.fa --cutoff=100 --supplementary-model=yan-et-al-2018 --mirnas=data/mature.fa --relative-cutoff=0 --input=ENCSR068MRQ.tsv

Note that only interactions expected to reach at least 100 pM under ideal conditions were considered in this model.
Occupant target_name miRNA Name Bound Fraction Efficiency
MIMAT0000076::ENST00000295926.7 CCNL1 hsa-miR-21-5p 36.31% 36.65%
MIMAT0000076::ENST00000526009.5 CLNS1A hsa-miR-21-5p 32.55% 32.91%
MIMAT0000076::ENST00000247843.6 YEATS4 hsa-miR-21-5p 32.5% 32.87%
MIMAT0000076::ENST00000361789.2 MT-CYB hsa-miR-21-5p 32.41% 32.78%
MIMAT0000076::ENST00000262507.10 COQ9 hsa-miR-21-5p 30.25% 35.45%
MIMAT0000076::ENST00000624234.3 EIF3L hsa-miR-21-5p 29.73% 30.11%
MIMAT0000076::ENST00000558814.1 MYO1E hsa-miR-21-5p 29.69% 30.08%
MIMAT0000076::ENST00000395719.7 G3BP2 hsa-miR-21-5p 29.67% 30.05%
MIMAT0000076::ENST00000409724.5 CAPG hsa-miR-21-5p 29.57% 29.95%
MIMAT0000076::ENST00000330029.6 UQCR10 hsa-miR-21-5p 29.54% 29.92%
MIMAT0000076::ENST00000295797.4 PRKCI hsa-miR-21-5p 29.34% 29.72%
MIMAT0000076::ENST00000265351.11 XPO5 hsa-miR-21-5p 29.17% 29.54%
MIMAT0000076::ENST00000355167.7 EYA4 hsa-miR-21-5p 28.94% 29.31%
MIMAT0000076::ENST00000261811.5 CYSTM1 hsa-miR-21-5p 28.93% 29.3%
MIMAT0000076::ENST00000569980.1 COQ9 hsa-miR-21-5p 25.86% 26.26%
MIMAT0000076::ENST00000422678.2 CFL2 hsa-miR-21-5p 25.78% 26.18%
MIMAT0000076::ENST00000469308.1 EIF1 hsa-miR-21-5p 24.61% 32.69%
MIMAT0000076::ENST00000493886.5 VCP hsa-miR-21-5p 20.87% 34.77%
MIMAT0000076::ENST00000375003.6 HP1BP3 hsa-miR-21-5p 20.71% 35.36%
MIMAT0000076::ENST00000426431.2 SP1 hsa-miR-21-5p 20.1% 28.98%
MIMAT0000076::ENST00000304734.9 RPL7L1 hsa-miR-21-5p 19.83% 35.15%
MIMAT0000076::ENST00000400935.2 XPOT hsa-miR-21-5p 19.64% 20.08%
MIMAT0000076::ENST00000496382.1 EIF4A2 hsa-miR-21-5p 19.62% 20.06%
MIMAT0000076::ENST00000409614.1 SERF2 hsa-miR-21-5p 19.62% 20.06%
MIMAT0000076::ENST00000267973.6 WDR61 hsa-miR-21-5p 19.62% 20.05%
MIMAT0000076::ENST00000533408.1 PTP4A2 hsa-miR-21-5p 19.61% 20.05%
MIMAT0000076::ENST00000539887.1 STRAP hsa-miR-21-5p 19.61% 20.04%
MIMAT0000076::ENST00000474223.1 SAT1 hsa-miR-21-5p 19.6% 20.04%
MIMAT0000076::ENST00000372715.6 WDR34 hsa-miR-21-5p 19.58% 20.02%
MIMAT0000076::ENST00000290349.10 CBR1 hsa-miR-21-5p 19.58% 20.02%
MIMAT0000076::ENST00000460911.5 EZH2 hsa-miR-21-5p 19.57% 20.01%
MIMAT0000076::ENST00000268802.9 NOB1 hsa-miR-21-5p 19.57% 20.01%
MIMAT0000076::ENST00000360830.8 RPS24 hsa-miR-21-5p 19.55% 19.99%
MIMAT0000076::ENST00000477460.6 SGK1 hsa-miR-21-5p 19.55% 19.98%
MIMAT0000076::ENST00000367242.3 TMEM183A hsa-miR-21-5p 19.52% 19.96%
MIMAT0000076::ENST00000451881.5 CUL4A hsa-miR-21-5p 19.52% 19.95%
MIMAT0000076::ENST00000491035.5 RPL10 hsa-miR-21-5p 19.5% 19.93%
MIMAT0000076::ENST00000369905.8 ACTR1A hsa-miR-21-5p 19.49% 19.93%
MIMAT0000076::ENST00000313511.7 TUFM hsa-miR-21-5p 19.46% 19.9%
MIMAT0000076::ENST00000340342.10 CTSL hsa-miR-21-5p 19.45% 19.89%
MIMAT0000076::ENST00000397441.6 PRMT5 hsa-miR-21-5p 19.45% 19.88%
MIMAT0000076::ENST00000350697.7 SEC13 hsa-miR-21-5p 19.42% 19.85%
MIMAT0000076::ENST00000557957.5 PDE8A hsa-miR-21-5p 19.34% 19.77%
MIMAT0000076::ENST00000316059.6 ZFP91 hsa-miR-21-5p 19.28% 19.71%
MIMAT0000076::ENST00000294785.9 NCSTN hsa-miR-21-5p 18.95% 35.77%
MIMAT0000076::ENST00000031146.8 SLC39A9 hsa-miR-21-5p 18.78% 25.75%
MIMAT0000680::ENST00000467810.1 TPR hsa-miR-106b-5p 18.38% 19.02%
MIMAT0000076::ENST00000539231.5 KLF5 hsa-miR-21-5p 18.33% 26.04%
MIMAT0000680::ENST00000309828.4 EIF3F hsa-miR-106b-5p 17.92% 18.55%
MIMAT0000680::ENST00000396136.6 ADAM10 hsa-miR-106b-5p 17.9% 18.53%

Download this view in TSV:

curl -H Accept:text/tab-separated-values 'https://major.iric.ca/~poirigui/cgi-bin/mirbooking-scan/app.cgi/cell-lines/ENCSR068MRQ'

Cite us

miRBooking 1.0: Weill N, Lisi V, Scott N, Dallaire P, Pelloux J, Major F. MirBooking simulates the stoichiometric mode of action of microRNAs, Nucleic Acids Res. 2015 43(14):6730-8.

miRBooking 2.0: Publication upcoming!